The heat-related effects of climate change are becoming increasingly apparent – along with their human toll in death and disease. WHO directors for non-communicable diseases and environment, climate change and health, Bente Mikkelsen and Maria Neira, are calling for the prevention of climate- and heat-related diseases to be included in the formal agenda of the COP 28 negotiations - "not just on the sidelines". July 2023 was the hottest month on record globally, with far-reaching impacts on human health. Extreme heat can lead to sudden organ failure and death. Chronic heat stress can also trigger or worsen several non-communicable diseases (NCDs) such as kidney disorders, hypertension, and cardiovascular and respiratory diseases, leading to premature deaths. In addition to heat, extreme weather events such as floods and storms also pose a risk to people living with NCDs when regular health services and access to life-saving medicines are disrupted. Displacement and trauma following extreme weather can also worsen mental health conditions. Nevertheless, non-communicable diseases such as those caused by heat and climate stress are not yet on the agenda of the 28th United Nations Climate Conference (COP28), which is scheduled to begin on November 30 in Dubai. while his hosts pledged to elevate health issues to the top. The WHO's directors for noncommunicable diseases and environment, climate change and health, Bente Mikkelsen and Maria Neira, are now pushing for the prevention of noncommunicable diseases caused by heat and other climate-related events to be part of the formal agenda of the COP 28 negotiations.